Currently in beta testing. Creates a fold-change connectome from two input connectomes, generally unfiltered. Must be node-aligned, from the same reference mapping, and unfiltered. ('edge' columns must contain identical entries, though not necessarily in the same order.)

DifferentialConnectome(connect.ref, connect.test, min.pct = NULL)

Arguments

connect.ref

A connectome from a system

connect.test

A connectome from a different system, to be compared to connect.ref

min.pct

Default NULL. Threshold to return clusterwise observations for both ligand and receptor. Only needs to be satisfied in connect.ref OR in connect.test.