DifferentialScoringPlot

Currently in beta testing. Creates x3 aligned heatmaps allowing visualization of ligand, receptor, and perturbation scores for a given cell-system of interest.

DifferentialScoringPlot(
  differential.connectome,
  features = NULL,
  sources.include = NULL,
  targets.include = NULL,
  min.score = NULL,
  min.pct = NULL,
  verbose = T,
  infinity.to.max = T,
  aligned = F
)

Arguments

differential.connectome	A differential connectome, made with DifferentialConnectome. May be filtered as desired prior to plotting.
features	Gene of interest. Output will be limited to edges including these specific genes.
sources.include	Source nodes of interest. Output will be limited to edges coming from these sources.
targets.include	Target nodes of interest. Output will be limited to edges landing on these targets.
min.score	Default NULL. Will limit output to edges with a differential score greater than this value.
min.pct	Default NULL. Threshold to return clusterwise observations for both ligand and receptor. Only needs to be satisfied in connect.1 OR in connect.2.
verbose	Whether to output feedback to user
infinity.to.max	Default TRUE. If TRUE, will create a pseudo value to replace values of "Inf"
aligned	Default FALSE. If TRUE, will create edge-aligned heatmaps (duplicate rows and columns in first two plots, to dimension map all three plots)